Human heart valves are anatomically perfectly adapted to their task. Therefore, heart valve transplants, so-called „homografts“, usually show very good long-term results.
Disadvantageous is that these grafts could be repelled by the recipient’s immune system. This leads to a loss of function of the graft and will eventually require another heart valve surgery.

In contrast, cell-free heart valves are not rejected by the recipient.
Cell-free human heart valves consist of tissue donations from which the cells of the donors are removed. Read more

The cell-free matrix can be used as a heart valve replacement and is spontaneously repopulated

after implantation by cells of the recipient.

Currently, corlife offers the following products:

Cell-free heart valves are based on tissue donations. Tissue donations cannot be planned.
Experience shows that predominantly aortic valves with a diameter of 21-25 mm, and pulmonary valves with a diameter of 23-26 mm are procured. The tissues are usually reserved for a patient within a few weeks after procurement.

Sizes & Availability

Cell-free heart valves are based on tissue donations. Tissue donations cannot be planned.
Experience shows that predominantly aortic valves with a diameter of 21-25 mm, and pulmonary valves with a diameter of 23-26 mm are procured. The tissues are usually reserved for a patient within a few weeks after procurement.

Diagnostic Imaging

After implantation there is no contraindication for diagnostic imaging like MRI, CT and ultrasound.

Medication

In most cases, no medication after transplantation is required.
There is a possibility that after implantation, the recipient might be treated with a medication suppressing blood clotting for a short period of time.